Saint Florentina was born in Cartagena, Spain, and was the sister of three bishops, St. Leander, St. Isidore of Seville, and St. Fulgentius. Losing their parents at an early age, Florentina was raised by her brother, St. Leander. Under his guidance she embraced the ascetic life. St. Leander founded a convent for her, where she became abbess as a cloistered nun.